Heart Physiology

The program of the course on physiology of the heart is compiled taking into account the state standard for teaching the basic course of physiology according to the undergraduate curriculum. An important feature of the course is the presentation of the material at different levels: a combination of molecular, cellular and systemic approaches in describing the functions of organs. The course presents basic and modern data on the functional features and histological structure of cardiomyocytes; formation of the action potential of various myocardial cells; fundamentals of myocardial mechanics, mechanisms of contraction and relaxation of cardiomyocytes; principles of intercellular interaction of myocardial cells; cellular electrophysiology in myocardial ischemia; mechanisms of action of cardiotropic pharmacological drugs; heart dysfunction.

Topic 1. Heart As an Element  of the Circulatory  System. Heart Function and Its Main Characteristics Topic 2. Heart Automaticity. Cardiac Conduction System Topic 3. Action Potential of the Working Myocardium and Its Physiological Consequences Topic 4. Electrocardiogram and Its Relationship with Electrophysiological Processes in the Heart Topic 5. Mechanisms of Regulation of Heart Activity Topic 6. Coronary Blood Flow. Myocardial Metabolism. Changes in the Activity of the Heart During Functional Loads